Akouos IPO Presentation Deck
June 2020, 48 slides
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background introduction to hearing the genetic medicine platform product candidate pipeline manufacturing | Akouos
the mission healthy hearing available to all therapies with the potential to restore improve and preserve high acuity hearing for people who live with disabling hearing loss | Akouos
genetic medicine platform focused on inner ear disorders | Akouos
experienced management team with otology genetic medicine and rare disease drug development | Akouos
deep pipeline highlights breadth of platform | Akouos
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diagnosis of hearing loss | Akouos
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overview of genetically driven hearing loss | Akouos
the anatomy and biology of the inner ear are ideal for one time genetic medicines | Akouos
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the precision genetic medicine platform | Akouos
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novel vector platform with library of vectors | Akouos
exhibits high transduction efficiency compared to other capsids | Akouos
dose tropism study in macaque showed efficient inner hair cell transduction at three weeks be | Akouos
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access to multiple cell types opens large target landscape | Akouos
multimodal capabilities create potential to address a broad range of monogenic and non monogenic inner ear disorders | Akouos
the global sing genetic hearing loss registry | Akouos
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our disciplined candidate selection criteria allow us to focus resources on promising targets covering a range of inner ear disorders a | Akouos
deep pipeline highlights breadth of platform | Akouos
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has the potential to address an unmet need for individuals with mediated hearing loss | Akouos
dual vector delivery of led to restoration of thresholds and long term hearing recovery in mice | Akouos
a single dose of restored cochlear function in mature mice lacking i | Akouos
planned phase clinical trial | Akouos
deep pipeline highlights breadth of platform | Akouos
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proof of concept data mediated delivery of recovered hearing in a knock out mouse model encoding human clarin can an | Akouos
our disciplined candidate selection criteria allow us to focus resources on promising targets covering a range of inner ear disorders ret | Akouos
deep pipeline highlights breadth of platform | Akouos
amen | Akouos
for the treatment of vestibular | Akouos
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key advantages to our manufacturing process | Akouos
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financial overview fidelity | Akouos
genetic medicine platform focused on inner ear disorders | Akouos
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board of directors and scientific advisory board ges | Akouos
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