AstraZeneca
in breast cancer ambition to eliminate breast cancer as a cause of death | AstraZeneca
Company
Deck Type
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Industry
Deck date
November 2023
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37 of 45
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February 2024
in breast cancer ambition to eliminate breast cancer as a cause of death | AstraZeneca
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combination with radiation exploring potential synergistic benefits to chemotherapy or radiation mediated mechanisms chemotherapy and radiation can have positive effects on anti cancer immunity both can directly induce tumor cell lysis and lead to immunogenic cancer cell death chemotherapy and radiation can enhance innate anti tumor immune responses however chemotherapy and radiation can also have negative effects on the immune system decreased lymphocyte and counts which can negatively impact response to therapy immune suppression due to increased in the tumor ongoing preclinical collaborations leverage specialized translational models to explore ability to augment chemotherapy radiation driven anti cancer mechanisms while countering the negative impacts cell death dis dar front a front trier cancer cancer res responses therapy | Alkermes
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