ATAI
was well tolerated with no dose limiting toxicities identified up to the highest dose of given every hours for days there were no serious adverse events reported nor discontinuations due to adverse events and both single and multiple ascending dose sad and mad regimens showed only mild adverse events that were comparable to placebo treated subjects no evidence of sedation or other side effects at any doses tested dose dependent increase in frontal beta power was demonstrated in subjects receiving but not with placebo providing evidence of target engagement and mechanism of action these results show potential use for as a clinically superior treatment for generalized anxiety disorder gad compared to and combination pharmacodynamic effect along lower incidence severity shows favorable profile | ATAI
Company
Deck date
October 2022
Slide
32 of 41
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