Nuvalent
preliminary safety profile favorable and consistent with alk selective sparing design of phase has not been identified transient asymptomatic grade increase treatment related adverse events in patients all treated patients grade grade grade any grade infrequent requiring dose any modification discontinued due to dose reduced due to overall avoiding related alt increased ast increased nausea constipation fatigue peripheral edema data cut off alt alanine ast aspartate creatinine dose limiting toxicity treatment related adverse event resulting in treatment discontinuation were grade alt grade ast elevations intolerable grade constipation occurred at following dose increase from resulting in dose reduction were grade alt ast elevation grade alt ast elevation grade nausea cognitive disturbance grade elevation grade treatment continues at the reduced dose for these patients source lin i | Nuvalent
Company
Deck date
January 2024
Slide
23 of 41
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