Nuvalent Investor Presentation Deck
October 2022, 31 slides
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post conference call presentation yin | Nuvalent
| Nuvalent
at the core built for patients driven by purpose | Nuvalent
next generation selective inhibitor in als | Nuvalent
a rationally designed kinase inhibitor for | Nuvalent
overcoming kinase selectivity in is and alk driven cancers a sol | Nuvalent
for positive advanced and other solid tumors resistance mutations | Nuvalent
preclinical exhibits potent activity across diverse fusion partners and resistance mutations | Nuvalent
preclinical is a brain penetrant selective inhibitor with the potential to avoid related adverse events | Nuvalent
safety and preliminary clinical activity of a highly selective inhibitor in patients with advanced fusion positive solid tumors cine | Nuvalent
study design a global phase study of in patients with advanced positive and other solid tumors cane | Nuvalent
cohort accrual phase dose | Nuvalent
phase population heavily solid tumors | Nuvalent
preliminary safety profile favorable and consistent with the highly selective sparing design of sore a sar | Nuvalent
exposure exceeded predicted efficacy thresholds | Nuvalent
preliminary efficacy induced tumor response across heavily patient populations see | Nuvalent
preliminary efficacy radiographic tumor regression observed across all dose levels | Nuvalent
time on treatment sustained duration with follow up ongoing and chemotherapy | Nuvalent
resistance mutations induced rapid responses in resistant patients erase a with tumor | Nuvalent
activity induced responses in intracranial lesions | Nuvalent
case study intracranial and extracranial activity in refractory bet | Nuvalent
ace | Nuvalent
pipeline | Nuvalent
pipeline ongoing programs | Nuvalent
for alk positive advanced and other solid tumors | Nuvalent
preclinical is a brain penetrant alk selective inhibitor with the potential to avoid related adverse events | Nuvalent
preclinical induced tumor regression across models of diverse alk single and compound resistance mutations | Nuvalent
| Nuvalent
for malignancies driven by her exon insertion mutations her | Nuvalent
preclinical is a brain penetrant her selective kinase inhibitor with potential to avoid adverse events related to inhibition | Nuvalent
targeted therapies for patients with cancer | Nuvalent
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